検索結果

Search Results for " G protein-coupled bile acid receptor "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T7428	SBI-115		GPCR19
	SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5		GPCR19
T4083	BAR501	BAR 501	GPCR19
	BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).		GPCR19
TQ0252	BAR502		FXR , GPCR19 , Autophagy
	BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).		FXR , GPCR19 , Autophagy
T4352	SB756050	SB-756050,SB 756050	GPCR19
	SB756050 is a specific TGR5 agonist.		GPCR19
T0843	Triamterene	Ademine,SKF8542	Sodium Channel , GPCR19
	Triamterene is a pteridinetriamine compound that inhibits SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS.		Sodium Channel , GPCR19
T8818	TC-G 1005		GPCR19
	TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.		GPCR19
T1824	TGR5 Receptor Agonist		GPCR19
	TGR5 is a potent TGR5(GPCR19) agonist.		GPCR19
T8752	BAR 501 impurity		GPCR19
	BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 impurity (10 μM) induces a 150% increase in luciferase act...		GPCR19
T63554	TGR5 Receptor Agonist 3
	TGR5 Receptor Agonist 3 is a G protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonist soft drug compound that decreases gallbladder filling, exhibits good gallbladder safety, and is able to act on hTGR5 (EC50: 16.4 ...
T60439	CAY10789
	CAY10789 (compound 6) is a potent CysLT1R (cysteinyl leukotriene receptor 1) antagonist with an IC50 of 2.80 μM. CAY10789 is also a GPBAR1 (G-protein-coupled bile acid receptor 1) agonist with an EC50 of 3 μM. CAY10789 s...

Compounds

Target: FXR, GPCR19, Autophagy

SB756050

T4352

Synonym: SB-756050,SB 756050

Target: GPCR19

Triamterene

T0843

Synonym: Ademine,SKF8542

Target: Sodium Channel, GPCR19

TGR5 Receptor Agonist

TGR5 Receptor Agonist 3

カタログ番号	製品名	別名	ターゲット
T5077	Deoxycholic acid sodium salt	Sodium deoxycholate,Sodium Desoxycholate	Endogenous Metabolite , GPCR19
	Deoxycholic acid sodium salt (Sodium deoxycholate) can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.		Endogenous Metabolite , GPCR19
T2965	Deoxycholic acid	Cholorebic,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic	Endogenous Metabolite , GPCR19
	Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorptio...		Endogenous Metabolite , GPCR19
T0700	Ursodeoxycholic acid	UDCA,Ursodiol	Potassium Channel , Endogenous Metabolite
	Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.		Potassium Channel , Endogenous Metabolite
T2968	Hyodeoxycholic acid	NSC 60672,α-Hyodeoxycholic Acid,HDCA	FXR , Endogenous Metabolite , GPCR19
	Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.		FXR , Endogenous Metabolite , GPCR19
T29078	Ursodeoxycholic acid sodium	UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium	FXR , Endogenous Metabolite , GPCR19
	Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it...		FXR , Endogenous Metabolite , GPCR19

天然物製品

Deoxycholic acid sodium salt

T5077

Synonym: Sodium deoxycholate,Sodium Desoxycholate

Target: Endogenous Metabolite, GPCR19

Deoxycholic acid

T2965

Synonym: Cholorebic,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic

Target: Endogenous Metabolite, GPCR19

Ursodeoxycholic acid

T0700

Synonym: UDCA,Ursodiol

Target: Potassium Channel, Endogenous Metabolite

Hyodeoxycholic acid

T2968

Synonym: NSC 60672,α-Hyodeoxycholic Acid,HDCA

Target: FXR, Endogenous Metabolite, GPCR19

Ursodeoxycholic acid sodium

T29078

Synonym: UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium

Target: FXR, Endogenous Metabolite, GPCR19

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPK-01411	Peptide Ready HLA-G&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can b...
TMPK-01418	Peptide Ready HLA-G&B2M Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can b...

Peptide Ready HLA-G&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01411

Species: Human

Expression System: HEK293 Cells

Peptide Ready HLA-G&B2M Monomer Protein, Human, MHC (His & Avi)

TMPK-01418

Species: Human

Expression System: HEK293 Cells